Search results for "genetics [Cerebellar Neoplasms]"

showing 10 items of 3028 documents

Composition en acides gras des hémisphères cérébraux de rats spontanément hypertendus allaités par des femelles Wistar

2003

Total lipid fatty acid composition was investigated in brain hemispheres of male Spontaneously Hypertensive Rats (SHR), compared with normotensive Wistar Kyoto rats (WKY) used as controls. Both strains were suckled by adoptive Wistar mothers, and then fed a standard diet after weaning. No difference was observed between the two hemispheres of WKY killed either at 10 or 30 days. In SHR killed at 10 days, the two hemispheres showed differences, SHR left hemispheres exhibiting greater fatty acid composition changes than those of WKY, phenomenon that toned down at 30 days. Hence, SHR pups showed a different total lipid fatty acid composition of their brain hemispheres when compared with their W…

medicine.medical_specialtyBrain chemistryGeneral Immunology and MicrobiologyCentral nervous systemGeneral MedicineBiologyGeneral Biochemistry Genetics and Molecular Biologymedicine.anatomical_structureEndocrinologyAnimal modelInternal medicineCerebral hemispheremedicineStandard dietWeaningFatty acid compositionWistar Kyoto RatsGeneral Agricultural and Biological SciencesComptes Rendus Biologies
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A mathematical model of cardiovascular dynamics for the diagnosis and prognosis of hemorrhagic shock

2020

Abstract A variety of mathematical models of the cardiovascular system have been suggested over several years in order to describe the time-course of a series of physiological variables (i.e. heart rate, cardiac output, arterial pressure) relevant for the compensation mechanisms to perturbations, such as severe haemorrhage. The current study provides a simple but realistic mathematical description of cardiovascular dynamics that may be useful in the assessment and prognosis of hemorrhagic shock. The present work proposes a first version of a differential-algebraic equations model, the model dynamical ODE model for haemorrhage (dODEg). The model consists of 10 differential and 14 algebraic e…

medicine.medical_specialtyCardiac outputMean arterial pressureShock HemorrhagicSettore ING-INF/01 - ElettronicaCardiovascular SystemGeneral Biochemistry Genetics and Molecular Biologycardiovascular dynamicshemorrhagic shockHeart RateInternal medicineHeart ratemedicineQuantitative assessmentAnimalsmathematical modellingCardiac OutputGeneral Environmental SciencePharmacologyGeneral Immunology and MicrobiologyMathematical modelbusiness.industryApplied MathematicsGeneral NeuroscienceSettore ING-IND/34 - Bioingegneria IndustrialeExperimental dataGeneral MedicineModels Theoreticalhemorrhagic shock;Blood pressureModeling and SimulationSettore ING-INF/06 - Bioingegneria Elettronica E InformaticaHemorrhagic shockCardiologybusinessMathematical Medicine and Biology: A Journal of the IMA
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Standardized Hemorrhagic Shock Induction Guided by Cerebral Oximetry and Extended Hemodynamic Monitoring in Pigs.

2019

Hemorrhagic shock ranks among the main reasons for severe injury-related death. The loss of circulatory volume and oxygen carriers can lead to an insufficient oxygen supply and irreversible organ failure. The brain exerts only limited compensation capacities and is particularly at high risk of severe hypoxic damage.This article demonstrates the reproducible induction of life-threatening hemorrhagic shock in a porcine model by means of calculated blood withdrawal. We titrate shock induction guided by near-infrared spectroscopy and extended hemodynamic monitoring to display systemic circulatory failure, as well as cerebral microcirculatory oxygen depletion. In comparison to similar models tha…

medicine.medical_specialtyCardiac outputSwineGeneral Chemical EngineeringHemodynamicsBlood withdrawalShock HemorrhagicGeneral Biochemistry Genetics and Molecular BiologyMicrocirculation03 medical and health sciences0302 clinical medicine030202 anesthesiologyInternal medicinemedicineAnimalsOximetryCardiac OutputCerebral oximetry030304 developmental biology0303 health sciencesSpectroscopy Near-InfraredGeneral Immunology and Microbiologybusiness.industryGeneral NeuroscienceHemodynamic MonitoringHemodynamicsBrainReference StandardsOxygenShock (circulatory)Hemorrhagic shockCirculatory systemCardiologymedicine.symptombusinessJournal of visualized experiments : JoVE
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Outcomes of hospitalized patients with COVID-19 according to level of frailty

2021

Background The complications from coronavirus disease 2019 (COVID-19) have been the subject of study in diverse scientific reports. However, many aspects that influence the prognosis of the disease are still unknown, such as frailty, which inherently reduces resistance to disease and makes people more vulnerable. This study aimed to explore the complications of COVID-19 in patients admitted to a third-level hospital and to evaluate the relationship between these complications and frailty. Methods An observational, descriptive, prospective study was performed in 2020. A sample of 254 patients from a database of 3,112 patients admitted to a high-level hospital in Madrid, Spain was analyzed. …

medicine.medical_specialtyComplicationsCoronavirus disease 2019 (COVID-19)lcsh:MedicineDiseaseGeneral Biochemistry Genetics and Molecular Biologylaw.invention03 medical and health sciences0302 clinical medicinelawStatistical significanceInternal MedicinemedicineCoronavirus infection030212 general & internal medicineMortalityProspective cohort studyAgedFrailtybusiness.industrySARS-CoV-2General NeuroscienceMortality ratelcsh:RCOVID-19General MedicinePrognosisIntensive care unitGeriatricsEmergency medicineDeliriumObservational studyPublic Healthmedicine.symptomGeneral Agricultural and Biological Sciencesbusiness030217 neurology & neurosurgery
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Quality-of-Life Impairment among Patients with Hidradenitis Suppurativa: A Cross-Sectional Study of 1795 Patients

2021

The chronic, inflammatory skin disorder hidradenitis suppurativa (HS) is associated well documented negative influences on patients&rsquo

medicine.medical_specialtyCross-sectional studyPopulationDiseaseDemographic dataArticleGeneral Biochemistry Genetics and Molecular Biology030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineQuality of lifeInternal medicineMedicineHidradenitis suppurativa030212 general & internal medicineDLQIlcsh:ScienceeducationEcology Evolution Behavior and Systematicseducation.field_of_studyintegumentary systembusiness.industryhidradenitis suppurativaPaleontologyDermatology Life Quality Indexmedicine.diseasehumanitiesquality of lifeSpace and Planetary ScienceCohortlcsh:QbusinessLife
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Associated factors to psychiatric morbidity in postmenopausal phases.

1998

Abstract Background: The greatest risk of psychiatric morbidity during the climacteric years is linked to a greater exposure to stressful life experiences, women's dissatisfaction with their role in society and to an absence of social backup. The question to be posed now is the extent to which the longitudinal surveys can confirm, refute or complement the results of the cross-sectional analyses. Methods: A study involving population-based cohorts was carried out on a sample of 120 women who had been previously identified as being premenopausal or menopausal during a cross-sectional examination conducted between 1987 and 1988 within the city of Valencia (Spain). The aims were to analyze the …

medicine.medical_specialtyCross-sectional studyPopulationGeneral Biochemistry Genetics and Molecular BiologyCohort StudiesLife Change EventsSocial supportConfidence IntervalsOdds RatioMedicineHumansPsychiatryeducationPsychiatric Status Rating Scaleseducation.field_of_studybusiness.industrySocial changeObstetrics and GynecologyGender IdentitySocial SupportOdds ratioMiddle AgedPostmenopauseCross-Sectional StudiesLogistic ModelsSocial ClassSpainFemalebusinessClimactericPsychosocialCohort studyFollow-Up StudiesMaturitas
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SAT0385 Lack of Correlation between Clinical and Ultrasonographic Evidence of Disease Activity in Psoriatic Arthritis:

2014

Background Musculoskeletal ultrasound (US) has been shown to be a sensitive tool to detect inflammation in inflammatory arthritides [1]. In practice, the composite clinical metric DAS28 is used as a feasible tool for measurement of disease activity, not only in rheumatoid arthritis but also for peripheral arthritis in psoriatic arthritis (PsA). Although both types of measures may reflect disease activity in inflammatory arthritis, some data have shown a poor correlation between clinical and US findings [2]. Objectives To compare clinical and US assessments of active disease in PsA patients. Methods In this cross sectional study PsA patients were consecutively recruited from an outpatient cl…

medicine.medical_specialtyCross-sectional studybusiness.industryInflammatory arthritisImmunologyArthritismedicine.diseaseGeneral Biochemistry Genetics and Molecular BiologyPsoriatic arthritisRheumatologyInternal medicineSynovitisRheumatoid arthritismedicinePhysical therapyImmunology and AllergyOutpatient clinicbusinessRheumatismAnnals of the Rheumatic Diseases
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Knowledge and attitudes towards smoking cessation counselling: an Italian cross-sectional survey on tertiary care nursing staff

2021

Background One of the most effective smoking cessation strategies involves care and advice from nurses due to their role in the front line of treatment. Lack of education on smoking cessation counselling may be detrimental, and adequate smoking cessation training during healthcare studies is needed. Objectives The study aimed to examine nurses’ attitudes, belief, and knowledge of smoking cessation counselling; knowledge of the health risks associated with smoking was also assessed. Design A cross-sectional survey on 77 nurses from the nursing staff of Cardiology, Cardiac Intensive Care and Surgical Oncology Units of two tertiary hospitals. Methods Cronbach’s alpha was calculated to assess …

medicine.medical_specialtyCross-sectional studymedicine.medical_treatmentNursingSmoking cessationGeneral Biochemistry Genetics and Molecular BiologySettore MED/01 - Statistica MedicaEducationSmoking cessation Counselling Education Training Tobacco-control Quit smokingCronbach's alphaSettore MED/28 - Malattie OdontostomatologicheQuit smokingIntensive careHealth caremedicineTrainingbusiness.industryGeneral NeuroscienceTobacco controlRGeneral MedicineScience and Medical EducationSettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheFamily medicineCoronary care unitSmoking cessationMedicineCounsellingPublic HealthGeneral Agricultural and Biological SciencesbusinessInclusion (education)Tobacco-controlPeerJ
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The comparison of cold-water immersion and cold air therapy on maximal cycling performance and recovery markers following strength exercises

2016

This study examined the effects of cold-water immersion (CWI) and cold air therapy (CAT) on maximal cycling performance (i.e. anaerobic power) and markers of muscle damage following a strength training session. Twenty endurance-trained but strength-untrained male (n = 10) and female (n = 10) participants were randomised into either: CWI (15 min in 14 °C water to iliac crest) or CAT (15 min in 14 °C air) immediately following strength training (i.e. 3 sets of leg press, leg extensions and leg curls at 6 repetition maximum, respectively). Creatine kinase, muscle soreness and fatigue, isometric knee extensor and flexor torque and cycling anaerobic power were measured prior to, immediately afte…

medicine.medical_specialtyDelayed onset muscle sorenessStrength trainingHydrostatic pressurelcsh:MedicineIsometric exerciseGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciences0302 clinical medicineDelayed onset muscle sorenessmedicineCreatine kinaseta315Leg pressdelayed onset muscle sorenessbiologyPower outputcreatine kinasebusiness.industryGeneral Neurosciencelcsh:R030229 sport sciencesGeneral MedicineKinesiologySurgerypower outputAnesthesiabiology.proteinCreatine kinasevoimaharjoitteluStrength trainingmedicine.symptomGeneral Agricultural and Biological SciencesCyclingbusinessAnaerobic exercise030217 neurology & neurosurgeryPeerJ
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The Effects of Oregano Oil on Fungal Infections Associated with Metabolic Syndrome

2020

International audience; This study aims to compare the evolution of mycosis associated with metabolic syndrome under allopathic treatment compared to phytotherapy using oregano essential oil. The study was conducted over a period of 6 months, on a total of 72 patients diagnosed with fungal infections associated with metabolic syndrome. The patients were divided into 3 groups, depending on the administered treatment: group 1: 24 patients who received allopathic treatment; group 2: 24 patients who received oregano oil treatment; group 3: control, which did not undergo any antifungal treatment. All three groups were subjected to specific diet therapy for mycosis. The patients were initially ev…

medicine.medical_specialtyDiet therapyItraconazoleMaterials Science (miscellaneous)010402 general chemistry01 natural sciencesGastroenterologyGeneral Biochemistry Genetics and Molecular Biologylaw.inventionFungal infectionsOregano oillawInternal medicineMaterials ChemistrymedicineGeneral Pharmacology Toxicology and PharmaceuticsMycosisProcess Chemistry and TechnologyGeneral EngineeringGeneral ChemistryGeneral Medicinemedicine.disease3. Good health0104 chemical sciencesNystatinTolerabilityMetabolic X syndrome[SDE]Environmental SciencesMetabolic syndromePhytotherapyFluconazolemedicine.drug
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